Biodefense Bioinformatics Blog

Friday, May 20, 2005

Multifactor Dimensionality Reduction (MDR) Software

An important question in biodefense research is whether DNA sequence variations can predict who is at risk for adverse events following vaccination for bioterroism agents such as smallpox. We have developed and released a multifactor dimensionality reduction (MDR) software package for detecting and characterizing combinations of DNA sequence variations that predict complex clinical endpoints. The Dartmouth Computational Genetics Laboratory (CGL) is pleased to announce the release of MDR 0.3 with many new features. Information about the MDR method can be found here. The open-source MDR software package can be downloaded for free here.

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